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The zones of the lung proposed by West in 1964,[1] divide the lung into three vertical regions, based upon the relationship between the pressure in the alveoli (PA), in the arteries (Pa), and the veins (Pv):
- #1: alveolar > arterial > venous
- #2: arterial > alveolar > venous
- #3: arterial > venous > alveolar
The ventilation/perfusion ratio is higher in zone #1 (the apex of lung when a person is standing) than it is in zone #3 (the base of lung.)
References
- ^ West J, Dollery C, Naimark A. "Distribution of blood flow in isolated lung; relation to vascular and alveolar pressures". J Appl Physiol 19: 713-24. PMID 14195584.
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